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LED Device Targets Cancer Cells, Spares Healthy Tissue

LED Device Targets Cancer Cells, Spares Healthy Tissue

Scientists have developed an LED-based therapy with tin oxide nanoflakes that eliminates up to 92% of skin cancer cells in lab tests, causing no harm to healthy tissue and providing a more affordable, targeted alternative to standard cancer treatments.

High-quality horizontal image of a lab setting where researchers developed an LED light that targets and kills cancer cells without damaging healthy tissue.

Source:

UT News - University of Texas at Austin

Breakthrough in Light-Driven Cancer Therapy

Scientists from The University of Texas at Austin and the University of Porto have introduced a new therapy using everyday LEDs and tin oxide (SnOx) nanoflakes. This approach selectively destroys cancer cells but spares healthy tissue. Testing in laboratory conditions showed the method eliminated up to 92% of skin cancer cells and 50% of colorectal cancer cells within 30 minutes of treatment (UT News, ScienceDaily).

How the Method Works

  • Utilizes near-infrared photothermal therapy (NIR-PTT).

  • Tin oxide nanoflakes absorb LED light and convert it into heat.

  • Heated nanoflakes cause thermal ablation of cancer cells.

No significant harm was observed in healthy skin cells, showing high precision (ACS Nano).

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Clear, vibrant image illustrating the LED device in use, highlighting its application in cancer research.

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Precision and Advantages of the LED-Nanoflake Approach

Why This Matters

This technique stands out compared to conventional photothermal therapies, which typically rely on expensive lasers and gold-based nanoparticles. LEDs are both affordable and portable, making advanced cancer treatment more accessible worldwide (UT Austin News). Tin, used for the nanoflakes, is cheaper and more abundant than precious metals usually used in nano-medicine.

Potential for Broader Access

  • May benefit low-resource settings lacking costly equipment.

  • Uses biocompatible, non-toxic materials.

  • Could allow future home-based or point-of-care therapies.

Well-lit image of the scientists involved in the study, inside a laboratory environment, showcasing the team behind the breakthrough LED treatment.

Source:

UT News - University of Texas at Austin

Next Steps and Future Prospects

What Comes Next

The LED-tin nanoflake therapy is currently in preclinical laboratory testing. Researchers will proceed to animal studies and, eventually, human trials. At this stage, the method has proven efficacy against skin and colorectal cancer cells only in vitro. Broader applications and regulatory approval may take years (ACS Nano).

Published Results and Collaboration

  • Findings published in peer-reviewed journal ACS Nano.

  • International collaboration under the UT Austin Portugal Program.

Experts highlight this technology’s potential to "democratize access to cancer treatment worldwide".

Next Steps and Future Prospects

What Comes Next

The LED-tin nanoflake therapy is currently in preclinical laboratory testing. Researchers will proceed to animal studies and, eventually, human trials. At this stage, the method has proven efficacy against skin and colorectal cancer cells only in vitro. Broader applications and regulatory approval may take years (ACS Nano).

Published Results and Collaboration

  • Findings published in peer-reviewed journal ACS Nano.

  • International collaboration under the UT Austin Portugal Program.

Experts highlight this technology’s potential to "democratize access to cancer treatment worldwide".

How does the LED light interact with SnOx nanoflakes to target cancer cells?

Near-infrared LED light is absorbed by the tin oxide nanoflakes, which heat up and destroy cancer cells through localized thermal ablation, sparing healthy tissue.

How does the LED light interact with SnOx nanoflakes to target cancer cells?

Near-infrared LED light is absorbed by the tin oxide nanoflakes, which heat up and destroy cancer cells through localized thermal ablation, sparing healthy tissue.

How does the LED light interact with SnOx nanoflakes to target cancer cells?

Near-infrared LED light is absorbed by the tin oxide nanoflakes, which heat up and destroy cancer cells through localized thermal ablation, sparing healthy tissue.

What are the potential side effects of this new LED-based cancer therapy?

What are the potential side effects of this new LED-based cancer therapy?

What are the potential side effects of this new LED-based cancer therapy?

How does this therapy compare to traditional chemotherapy in terms of effectiveness and safety?

How does this therapy compare to traditional chemotherapy in terms of effectiveness and safety?

How does this therapy compare to traditional chemotherapy in terms of effectiveness and safety?

What are the next steps for clinical trials of this LED-based cancer therapy?

What are the next steps for clinical trials of this LED-based cancer therapy?

What are the next steps for clinical trials of this LED-based cancer therapy?

How accessible will this therapy be for patients in underserved regions?

How accessible will this therapy be for patients in underserved regions?

How accessible will this therapy be for patients in underserved regions?

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