Kailera Therapeutics secures $600 million in Series B funding to advance global Phase 3 studies of its obesity drug KAI-9531, a dual GLP-1/GIP agonist with strong clinical results.
October 14, 2025
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Kailera Therapeutics
Massive Investment in Obesity Drug Research
Kailera Therapeutics has closed a landmark $600 million Series B round to propel its next-generation obesity drug KAI-9531 into global Phase 3 trials. The financing was led by Bain Capital Private Equity and included major investors like Adage Capital, CPP Investments, Qatar Investment Authority, and Royalty Pharma, reflecting sustained investor confidence in obesity therapeutics. (source)
Key Stakeholders
Bain Capital Private Equity (lead)
Adage Capital
CPP Investments
Qatar Investment Authority
Royalty Pharma
Atlas Venture
RTW Investments
Sirona Capital
Analysts note this sum as one of the top biotech financings in 2025, emphasizing the ongoing investment trend in obesity drug development. (Endpoints News)
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KAI-9531: Clinical Results and Pipeline Scope
Drug Mechanism and Trial Data
KAI-9531 is a dual GLP-1/GIP receptor agonist that acts on two metabolic hormone pathways. In a major Phase 3 study in China, the drug demonstrated a 17.7% average weight loss compared to placebo over 48 weeks. Notably, 88% of participants lost at least 5% of their body weight, and 44.4% achieved at least 20% weight reduction. (Fierce Biotech)
Upcoming Trials
Study of adults with BMI ≥ 35 kg/m²
Two separate trials for overweight/obese individuals with and without type 2 diabetes
Kailera is also developing oral obesity drugs, marking a diverse portfolio in metabolic health therapies.
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