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LillyDirect, Walmart Partner for In-Store Zepbound Access

LillyDirect, Walmart Partner for In-Store Zepbound Access

Eli Lilly collaborates with Walmart to offer Zepbound, an obesity medication, for direct-to-consumer pick-up pricing at Walmart pharmacies, expanding nationwide access and lowering patient costs.

Exterior view of a Walmart Pharmacy, representing the new LillyDirect retail pick-up option collaboration.

Source:

Eli Lilly and Co.

New Pharmacy Pickup Option for Obesity Medication

Eli Lilly and Walmart have launched a new program allowing patients to collect Zepbound (tirzepatide) at Walmart pharmacies nationwide, starting mid-November 2025. This initiative is the first time consumers can access LillyDirect’s direct-to-consumer pricing for Zepbound vials through a physical retail outlet (PRNewswire).

Direct-to-Consumer Pricing Model

  • Price starts at $349/month for the lowest dose of Zepbound.

  • Patients need a valid prescription to qualify for self-pay pricing.

  • This price reflects a 50% or greater discount versus list prices of other GLP-1 drugs used for obesity (Fierce Healthcare).

The self-pay method means no need for insurance coverage, granting access to individuals whose insurance may not cover weight loss treatments.

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Pharmacist assisting a customer inside a Walmart Pharmacy, depicting accessibility and service.

Source:

Walmart Inc.

Strategic Collaboration Details

Walmart brings its 4,600 pharmacy locations into the program, increasing geographic reach and making Zepbound accessible to millions more Americans battling obesity (iHeart).

Obesity and Diabetes Drug Market Impact

  • LillyDirect’s rapid growth: Already responsible for 35% of new Zepbound scripts in Q2 2025.

  • Competitive landscape: This partnership strengthens Eli Lilly’s position against Novo Nordisk and other major competitors.

How to Access

  1. Obtain a valid Zepbound prescription.

  2. Order via the LillyDirect platform.

  3. Pick up the medication at the nearest Walmart pharmacy—no insurance required.

Screenshot of the LillyDirect platform showing prescription ordering features.

Source:

Eli Lilly and Co.

Accessibility and Broader Implications

This collaboration aligns with direct-to-consumer healthcare trends and federal efforts to improve access, reduce barriers, and cut financial burdens for patients (PRNewswire).

Product Background

  • Zepbound is a GLP-1 receptor agonist for adults managing obesity or weight-related conditions.

  • The medication must be used with a reduced-calorie diet and physical activity for effective results.

With insurance coverage still varying, this new self-pay model provides a cost-effective alternative for many patients and may lead to similar ventures in retail pharmacy access for weight loss drugs (Fierce Healthcare).

Accessibility and Broader Implications

This collaboration aligns with direct-to-consumer healthcare trends and federal efforts to improve access, reduce barriers, and cut financial burdens for patients (PRNewswire).

Product Background

  • Zepbound is a GLP-1 receptor agonist for adults managing obesity or weight-related conditions.

  • The medication must be used with a reduced-calorie diet and physical activity for effective results.

With insurance coverage still varying, this new self-pay model provides a cost-effective alternative for many patients and may lead to similar ventures in retail pharmacy access for weight loss drugs (Fierce Healthcare).

How does the self-pay pricing for Zepbound compare to other GLP-1 medications?

Zepbound’s self-pay price through LillyDirect at Walmart is at least 50% lower than the list price of other GLP-1 medicines for obesity.

How does the self-pay pricing for Zepbound compare to other GLP-1 medications?

Zepbound’s self-pay price through LillyDirect at Walmart is at least 50% lower than the list price of other GLP-1 medicines for obesity.

How does the self-pay pricing for Zepbound compare to other GLP-1 medications?

Zepbound’s self-pay price through LillyDirect at Walmart is at least 50% lower than the list price of other GLP-1 medicines for obesity.

What are the benefits of using LillyDirect over traditional insurance-based options?

What are the benefits of using LillyDirect over traditional insurance-based options?

What are the benefits of using LillyDirect over traditional insurance-based options?

How will this collaboration impact the market for obesity and diabetes drugs?

How will this collaboration impact the market for obesity and diabetes drugs?

How will this collaboration impact the market for obesity and diabetes drugs?

What are the patient reviews and experiences with LillyDirect so far?

What are the patient reviews and experiences with LillyDirect so far?

What are the patient reviews and experiences with LillyDirect so far?

How does the $349 monthly price for Zepbound compare to other weight loss treatments?

How does the $349 monthly price for Zepbound compare to other weight loss treatments?

How does the $349 monthly price for Zepbound compare to other weight loss treatments?

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